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PLoS Medicine: New Articles

Why Current Publication Practices May Distort Science
John Ioannidis and colleagues argue that the current system of publication in biomedical research provides a distorted view of the reality of scientific data.
Faecal and Urinary Incontinence after Multimodality Treatment of Rectal Cancer
Marilyne Lange and Cornelis van de Velde discuss the differential diagnosis and management of incontinence after rectal cancer treatment.
SLC2A9 Is a High-Capacity Urate Transporter in Humans
Mark Caulfield and colleagues show that the SLC2A9 gene, which encodes a facilitative glucose transporter, is also a high-capacity urate transporter.

EurekAlert! - Biology

Astrocytes and synaptic plasticity
Mon, 13 Oct 2008 00:00:00 -0400
(Rockefeller University Press) By mopping up excess neurotrophic factor from neuronal synapses, astrocytes may finely tune synaptic transmission to affect processes such as learning and memory, say Bergami et al. Their report is published in the Journal of Cell Biology.
Body's anti-HIV drug explained
Sun, 12 Oct 2008 00:00:00 -0400
(University of Southern California) Study in journal Nature reveals atomic structure of enzyme capable of repelling HIV virus, suggesting new approach for drug development.
Pectin power
Sun, 12 Oct 2008 00:00:00 -0400
(Norwich BioScience Institutes) Scientists from the UK's Institute of Food Research have found a new possible explanation for why people who eat more fruit and vegetables may gain protection against the spread of cancers.They have shown that a fragment released from pectin, found in all fruits and vegetables, binds to and is believed to inhibit galectin 3, a protein that plays a role in all stages of cancer progression.

 
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Websites

Ambit Biosciences - Small molecule drug development using proprietary technology to screen interactions with human proteins, in target-specific programs to present as clinical-stage compounds. Profile of company based in San Diego, California.
Meta Description: [ Ambit Biosciences ]

Matritech - Developer of proteomics-based diagnostic products for the early detection of cancer by identifying proteins correlated with breast, bladder, prostate, cervical and colon cancers. Located in Newton, Massachusetts.
Meta Description: [ Matritech is a leading developer of proteomics-based diagnostic products for the early detection of cancer. Using its patented proteomics technology, Matritech has identified proteins correlated with breast, bladder, prostate, cervical and colon cancers. Matritech is one of the first companies to... ]

NextGen Sciences - Provider of integrated solutions for protein research in expression markers, at Philadelphia and Alconbury. England.

Proteome Systems Ltd. - Specializes in interpretation of 2-dimensional gels, and developing point-of-care diagnostics in the areas of cystic fibrosis, cancer, infectious disease and aging. Includes alpha-amylase test, and research programs, with contacts in USA, Japan and headquarters in Sydney, Australia.


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